Chromgen-reagent test system

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase

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422 56, 422 61, 435 28, 435184, 435810, 436 66, 436169, G01N 2100, G01N 3372, C12Q 128, C12N 999

Patent

active

057029130

ABSTRACT:
An improved chromogen-reagent test system for a slide, test kit or the like has particular utility in the testing of fecal specimens for occult blood. The chromogen-reagent system may include the use of colorless guaiac which, in the presence of a developing solution and a catalyst, is oxidized to yield a predetermined color such as blue. Hydrogen peroxide is used as the developing solution and hemoglobin in the fecal specimen functions as the catalyst. The chromogen-reagent test system includes an indicator area for determining if the guaiac and the developing solution are functioning properly, i.e., the test system of the present invention verifies that the guaiac has not lost its activity nor been improperly catalyzed and that the hydrogen peroxide has not lost its activity. The indicator area includes a catalyst which has a greater stability than blood, in respect to adverse environmental conditions, such that a determination can be made if the reagents are functioning properly.

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