Chromenone and chromanone derivatives as integrin inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S385000, C514S456000, C548S331500, C546S268100, C549S406000

Reexamination Certificate

active

06849646

ABSTRACT:
The invention relates to compounds having formula (I), wherein R1, R2, R3, R4, R5, R7, R8, R11, Z, m and n have the meaning cited in claim 1, and to the physiologically acceptable salts and solvates which can be used as integrin inhibitors, especially in the prophylaxis and treatment of circulatory diseases, in case of thrombosis, myocardial infarction, coronary heart diseases, arteriosclerosis, osteoporosis, pathologic processes caused or propagated by angiogenesis and in tumor therapy.

REFERENCES:
patent: 5703075 (1997-12-01), Gammill
patent: 341 104 (1989-11-01), None
patent: 90 06921 (1990-06-01), None
patent: 91 19707 (1991-12-01), None
patent: 96 22288 (1996-07-01), None

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