Chromene derivatives and salts thereof, and pharmaceuticals cont

Details Chromene derivatives and salts thereof, and pharmaceuticals cont Chromene derivatives and salts thereof, and pharmaceuticals cont

1998-09-29

2000-09-26

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549407, A61K 31353, C07D31160

Patent

active

061243477

ABSTRACT:
Disclosed are chromene derivatives represented by the following formula: ##STR1## wherein R.sup.1 s represent alkyl, alkoxy or like groups, R.sup.2 represents a hydrogen atom or an alkyl group, R.sup.3 represents a substituted or unsubstituted phenyl, naphthyl or heterocyclic group, and m stands for an integer of from 0 to 4, and their salts; and pharmaceuticals containing them as effective ingredients. The chromene derivatives and their salts show excellent AGE formation inhibitory action and are useful as preventives and therapeutics for diabetic complications.

REFERENCES:
Patent Abstract of Japan, vol. 97, No. 6, Jun. 30, 1997, JP 09 040626, Feb. 10, 1997.
Patent Abstract of Japan, vol. 97, No. 7, Jul. 31, 1997, JP 09 059233, Mar. 4, 1997.

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