Chromatography ligand

Details Chromatography ligand Chromatography ligand

2011-01-11

2011-01-11

Haq, Shafiqul (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is organic

C436S524000, C436S529000, C436S530000, C435S287200, C564S305000

Reexamination Certificate

active

07867784

ABSTRACT:
The present invention relates to a chromatography ligand defined by the following formula (I) R1—R2—N(R3)—R4—R5wherein R1is a substituted or non-substituted phenyl group; R2is a hydrocarbon chain comprising 0-4 carbon atoms; R3is a hydrocarbon chain comprising 1-3 carbon atoms; R4is a hydrocarbon chain comprising 1-5 carbon atoms; and R5is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.

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