Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Reexamination Certificate
2011-07-05
2011-07-05
Nguyen, Bao-Thuy L (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
C436S514000, C436S164000, C436S169000, C436S524000, C436S529000, C436S530000, C436S805000, C436S810000, C435S287100, C435S287200, C435S287700, C435S287900, C435S970000, C435S805000, C435S810000, C422S420000, C422S422000, C422S425000, C422S427000, C422S430000
Reexamination Certificate
active
07972872
ABSTRACT:
This invention provides an immunochromatography detection apparatus exhibiting excellent convenience, sensitivity, and specificity, a detection method therefore, a kit using the same, and a method for producing such apparatus and kit, by constructing a solid-phase support, on which the conditions for the reaction wherein an analyte specifically binds to a labeled reagent containing a ligand that specifically binds to the analyte and those for the reaction wherein a capture reagent specifically binds to a complex of the analyte and the labeled reagent in the immunochromatography detection method are continuously optimized, and the pretreated specimens are optimized for such reactions. This chromatography detection apparatus comprises: a sheet-like solid-phase support; a specimen-supply site thereon at which a specimen deduced to contain at least an analyte or a mixture of such specimen and a labeled reagent containing a ligand that specifically binds to the analyte is supplied; and a capture reagent site to which a capture reagent capable of specifically binding to and capturing a complex of the analyte and the labeled reagent has been immobilized, wherein at least one functional site having a particular or multiple functions is provided between the specimen-supply site and the capture reagent site.
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Ito Hiromi
Shida Ryo
Bent Stephen A.
Denka Seiken Co., Ltd.
Foley & Lardner LLP
Nguyen Bao-Thuy L
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