Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1986-09-29
1990-10-02
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
422 56, 422 58, 422 61, 422 69, 422 70, 435 7, 435805, 436162, 436501, 436514, 436518, 436530, 436807, 436810, C12Q 168, G01N 33543, G01N 33548, G01N 33558
Patent
active
049606913
ABSTRACT:
A test strip for analysis of analytes such as antigens, antibodies or polynucleotides employs a chromatographic medium and a solvent capable of transporting reagents and/or sample. Reagents are selected and disposed on the medium such that a labeled (first) reagent arrives at the detection (third) zone only after analyte is immobilized there and non-reactive sample componets have been transported beyond the detection zone. This sequential arrival is accomplished by the relative mobility of the reagent or sample; or by the site relationship of the zones. Preferably, the site relationship of the sample (second) zone and the label (first) zone is such that a plurality of pathways guide the sample and labeled reagent and any subsequent reagents to the detection zone in the recited order. Single and multiple pathway devices are disclosed.
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Ching Shanfun
Gordon Julian
McMahon Michael E.
Abbott Laboratories
Brainard Thomas D.
Corneglio Donald L.
Kepplinger Esther L.
Saunders David A.
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