Chromatographic separation using ion-exchange resins

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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210656, 2101982, 2105021, 127 462, 127 463, B01D 1508

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active

052214788

ABSTRACT:
This invention is a process for the chromatographic separation of a fluid mixture in which the mixture is contacted with an ion-exchange resin, eluted through the resin under conditions such that the rate of passage of one component of the mixture through the resin bed is retarded relative to the rate of passage of a second component of the mixture, and a first product stream rich in said first component and a second product stream rich in said second component are recovered. The invention involves the use of an ion-exchange resin made from a copolymer which is prepared in a multi-stage polymerization process. The use of this resin is found to provide fast separation kinetics and increases the overall speed and efficiency of the separation. This invention is particularly suited for fructose/glucose separations in the preparation of high fructose corn syrup.

REFERENCES:
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patent: 4267054 (1981-05-01), Yoritomi et al.
patent: 4419245 (1983-12-01), Barrett et al.
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patent: 4564644 (1986-01-01), Harris
patent: 4724082 (1988-02-01), Boom
Ghim et al., Adsorption Characteristics of Glucose and Fructose in Ion-Exchange Resin Columns, Ind. Eng. Chem. Fundam., 1982, 21, pp. 369-374.
Welstein et al., Separation of Glucose and Fructose: Effects of Resin Characterstics on Separation, Ion Exchange Technology, pp. 463-471, Chichester, England, 1979.
John Wiley, Mike's Laboratory Handbook of Chromatography and Allied Methods, New York, 1979, pp. 276-277 and 286-287.
Barker et al., Separation of Fructose from Carbohydrate Mixtures by Semicontinuous Chromatography, Chemical Industries, p. 817, Nov. 17, 1983.

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