Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-09-09
1986-12-16
Therkorn, Ernest G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
424 60, 435 77, 435280, 435803, 536 173, C07H 1526, B01D 1508
Patent
active
046297928
ABSTRACT:
An in vitro enzymatic process which efficiently converts (+,-)-tropicamide to essentially pure (+), (-)-tropicamide O-.beta.-D-glucuronide. This product is then separated, advantageously, into the novel compounds (+)-tropicamide O-.beta.-D-glucuronide and (-)-tropicamide O-.beta.-D-glucuronide. The products disclosed herein absorb ultraviolet light, and, thus, can be incorporated into suitable plastic films which are then useful for screening out harmful ultraviolet radiation for the protection of packaged goods. Also, the products can be used to protect the skin against burning by sunlight.
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Ando, et al., Synthesis of Mycophenolic Acid .beta.-D-Glucuronide and its Antitumor Activity, J. Antibiotics, 23, 408-413 (1970).
Johnson, et al., Glucuronidation of Lipophilic Substrates, Prep. Biochem. 9, 391-406 (1979).
Fraser Thomas H.
Herlihy Walter C.
Repligen Corporation
Saliwanchik Roman
Therkorn Ernest G.
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