Chromatographic purification of maytansine

Details Chromatographic purification of maytansine Chromatographic purification of maytansine

1977-12-07

1979-03-20

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D41314

Patent

active

041453450

ABSTRACT:
There is provided a high yield mode of separating maytansine from other maytansinoid components associated therewith in extracts thereof from natural sources. The procedure comprises two sequential chromatographic steps on silica gel in different solvent systems.

REFERENCES:
patent: 3896111 (1975-07-01), Kupchan et al.

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