Chromatographic determination of ions

Details Chromatographic determination of ions Chromatographic determination of ions

1991-02-08

1992-12-01

Theisen, Mary Lynn

Liquid purification or separation

Processes

Chromatography

2101982, 422 70, 436161, B01D 1508

Patent

active

051678276

ABSTRACT:
Herein described is a process for the chromatographic determination of ions, particularly anions on a reversed-phase column, in which sample ions are introduced into a mobile phase containing a modifier and a counterion, the mobile phase with the modifier, counterion and sample ions is passed through the column and, after separation with the aid of a suitable detection method, preferably an indirect UV-detection method, the individual sample ions are determined quantitatively via the decrease the counterion concentration in the eluent. In this process the mobile phase is a mixture of water an an organic solvent and has a pH-value of more than 5. The modifier used is a quaternary ammonium hydroxide of formula ##STR1## in which at least one radical is a straight-chained or branched alkyl radical with at least 8 and up to 20, more particularly 12 to 18 C-atoms. Prior to the passage of the mobile phase containing the sample ions, the reversed-phase column is preferably brought into equilibrium with the modifier, particularly with the modifier and the counterior. Trimethyl hexadecyl ammonium hydroxide is preferable used as the quaternary ammonium hydroxide. Also described herein is the use of said quaternary ammonium hydroxides for the quantitative chromatographic determination of ions and in particular for the determination of inorganic anions, as well as a reversed-phase material chromatographic column obtained through the conditioning with the modifier.

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