Chromatographic column packing having a bonded organosiloxane co

Compositions – Preservative agents – Anti-oxidants or chemical change inhibitants

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252429R, 210656, 2101982, 55 67, 55386, B01J 3102, B01J 4900

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active

042422272

ABSTRACT:
Improved packings for columns useful in gas chromatography are made by a multistep process whereby polysiloxane molecules having various organic substituents are chemically bonded to the surface of a siliceous support. The process comprises one or more cycles of successive reactions with an activated support surface of silicon tetrachloride, an organic dichlorosilane, silicon tetrachloride a second time, a polysiloxane polyol, with intermediate hydrolyses where appropriate to provide reactive terminal silanol groups and a final capping reaction with an organic monochlorosilane. The packing as so prepared is further improved by coating with a conventional stationary phase.

REFERENCES:
patent: 3722181 (1973-03-01), Kirkland
Kirkland, J. Chromatogr. Sci., 8, 309, (1970), and 9, 206, (1971).
Locke, J. Chromatogr. Sci., 11, 120-128, (1973).
Aue et al., J. Chromatogr. Sci., 42, 319-335, (1969).
Hastings et al., J. Chromatogr., 60, 329-344, (1971).
Majors et al., J. Chromatogr. Sci., 12, 767-778, (1974).
Grushka et al., Anal. Chem., 49, 1005A-1008A, 1010A, 1012A, (1977).

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