Chromatographic cassette

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435810, 435 77, 435 791, 435 792, 436162, 436514, 422 56, 422 58, 422 70, 210658, 2101983, 210 95, G01N 3353, G01N 33558, G01N 3090, G01N 3002

Patent

active

049992856

ABSTRACT:
A chromatographic device is disclosed. The device comprises in combination a housing, a strip of bibulous material non-removably confined in the housing. The strip has a length and width only slightly less than the length and width of the inner walls of the housing. The inner walls of the housing have means attached thereto for supportively confining the strip in the housing. The strip is confined so that (1) the front and back of the strip are essentially free from contact with the walls of the housing and (2) the capillary action of the strip remains substantially unchanged, and (3), where the strip is paper, the strip is allowed to expand as it is traversed by the liquid medium. The bottom end of the housing contains means for enabling contact of a portion of the strip with the liquid medium. The housing further contains means for visually observing the strip and can also contain indicating means cooperative therewith to assist in determining the result of a chromatographic test. The present device has particular application in immunochromatography for the determination of the presence of an analyte suspected of being present in a sample.

REFERENCES:
patent: 3510263 (1970-05-01), Hach
patent: 3620677 (1971-11-01), Morison
patent: 3623602 (1971-11-01), Valente
patent: 4168146 (1979-09-01), Grubb et al.
patent: 4298688 (1981-11-01), Kallies
patent: 4361537 (1982-11-01), Deutsch et al.
patent: 4428908 (1984-01-01), Ashley et al.
patent: 4435504 (1984-03-01), Zuk et al.
patent: 4517288 (1985-05-01), Giegel et al.

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