Chroman carboxylic acid derivatives for the treatment of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S235000

Reexamination Certificate

active

07446127

ABSTRACT:
There are disclosed derivatives of 3-chromancarboxylic acid represented by formula Itheir pharmaceutically acceptable salts thereof and prodrugs thereof which are useful for treatment and control of non-insulin dependent diabetes mellitus (type II diabetes) and its related vascular disease as well as obesity and lipid disorders.

REFERENCES:
patent: 5639771 (1997-06-01), Obata et al.
patent: 06-32957 (1994-11-01), None
patent: WO 01/26656 (2001-04-01), None
Lei Tang, Juanhong Yu, Ying Leng, Ying Feng, Yushe Yang and Ruyun Ji, “Synthesis and Insulin-Sensitizing Activity of a Novel Kind of Benzopyran Derivative”, Bioorganic & Medicinal Chemistry Letters 13 (2003) 3437-3440.
R. J. Jarett, “Type 2 (non-insulin-dependent) diabetes mellitus and coronary heart disease- chicken, egg or neither?”, Diabetologia, 1984, 26: 99-102.

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