Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1990-12-11
1992-03-24
Griffin, Ronald W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
514456, 514458, 514474, 514824, 514 25, A61K 3135
Patent
active
050990128
ABSTRACT:
Conjugates of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid with p-aminophenylsaccharides, with aminoalkyl-derivatized dextrans and with polylysines and polyornithines are prepared by condensation using diimides. Methods and compositions for the use of such conjugates to protect mammals from reperfusion injury are also disclosed.
REFERENCES:
patent: 4401661 (1983-08-01), Schaub et al.
patent: 4877810 (1989-10-01), Mickle et al.
Mickle et al. Ann. Thorac. Surg. 47, 553-557 (1989), "Myocardial Salvage with Trolox and Ascorbic Acid for an Acute Evolving Infarction".
Taylor et al., J. Am. Oil Chem. Soc. 58, 622-626 (1981), "Antioxidant Activity of Amino Acids Bound to Trolox-C.RTM.".
Schacht et al., J. Controlled Release 1, 33-46 (1984), "Polymer-Drug Combinations: Synthesis and Characterization of Modified Polysaccharides Containing Procainamide Moieties".
Molteni, Methods in Enzymology 112, 285-298 (1985), "Dextran and Inulin Conjugates as Drug Carriers".
Arnold, Methods in Enzymology 112, 270-285 (1985), "Polylysine-Drug Conjugates".
Mickle Donald A. G.
Wu Tai-Wing
DuPont Paul E.
Eastman Kodak Company
Griffin Ronald W.
Hansen Philip E.
LandOfFree
Chroman-2-carboxamide conjugates and their use for treatment of does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chroman-2-carboxamide conjugates and their use for treatment of , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chroman-2-carboxamide conjugates and their use for treatment of will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2011543