Chondrosarcoma associated genes

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S300000

Reexamination Certificate

active

09819144

ABSTRACT:
The invention features a nucleic acid molecule encoding a chondrosarcoma associated polypeptide and methods for diagnosing patients with chondrosarcoma. the gene.

REFERENCES:
patent: 4873191 (1989-10-01), Wagner et al.
patent: 5175384 (1992-12-01), Krimpenfort et al.
patent: 5175385 (1992-12-01), Wagner et al.
patent: 5677143 (1997-10-01), Gaynor et al.
patent: 5708158 (1998-01-01), Hoey
patent: 5744343 (1998-04-01), Draetta et al.
Bowie, et al. Science, vol. 247: 1306-1310, 1990.
Lazar, et al. Mol. Cell. Biol., 8(3): 1247-1252, 1988.
Burgess, et al. J. Cell Biol. 111: 2129-2138, 1990.
Ngo et al., in“The Protein Folding Problem and Tediary Structure Prediction”, 1994, Merz, et al. (ed.), Birkhauser, Boston, MA, pp. 433, and 492-495.
Skolnick et al., From genes to protein structure an function: novel applications of computational approaches in the genomic era, Trends in Biotech. 18: 34-39, 2000.
Alberts et al. Molecular Biology of the Cell, 3rd Edition, 1994, p. 465.
Greenbaum et al., Genome Biology, 2003, vol. 4 (9), pp. 117.1-117.8.
Mallampalli et al., Biochem. J. 1996, vol. 38, pp. 333-341.
Fu et al., EMBO journal, 1996, vol. 15, pp. 4392-4401.
Nawa et al. Int. J. Cancer, 1996, 69(2): 86-91.
Bowie et al., Deciphering the Message in Protein Sequences: Tolerance to Amino Acid SubstitutionsScience, 247:1306-1310.
Burgess et al., “Possible Disassociation of the Heparin-binding and Mitogenic Activities of the Heparin-binding (Acidic Fibroblast) Growth Factor-1 from its Receptor-binding Activities by Site-directed Mutagenesis of a Single Lysine Residue,” J. of Cell Bio., 111:21.
Chen et al., “Intracellular Antibodies as New Class of therapeutic Molecules for Gene Therapy,” 1994, Hum. Gene Ther., 5:595-601.
Czubayko et al., “Construction of Ribozyme Directed Against Interleukin-6 mRNA: Evaluation of Its Catalytic Activity In Vitro and In Vivo,” 1994, Blood, 84:3758-65.
Gerhard, “Fusion of Cells in Suspension and Outgrowth of Hybrids in Conditioned Medium,” Monoclonal Antibodies, Plenum Press, 1980, 370-371.
GENBANK Accession No. AF002996.
Ghose et al., “Preparation of Anti-body Linked Cytotoxic Agents,” Methods in Enzymology, 93: 326-327, 1983.
Glockner G. et al., “Genomic Sequence Around the CP1 Gene,” EMBL Database Entry 11SAF2996: Accession No. AF002996, May 27, 1997.
Gordon, “Transgenic Animals,” Intl. Rev. Cytol. 115:171-229, 1989.
Gu et al., “Deletion fo DNA Polymerase β Gene Segment in T Cells Using Cell Type-specific Gene Targeting,” Science, 265:103, 1984.
Hammer et al., “Production of transgenic rabbits, sheep and pigs by microinjection,” Nature, 315:680.
Kobayashi et al., “Reversal of Drug Sensitivity in Multidrug-Resistant Tumor Cells by anMDRI(PGYI) Ribozyme,” 1994, Cancer Res. 54:1271-1275.
Kraemer et al., “Genetic Maipulation of the Early Mammalian Embryo,” Banbury Report, Cold Spring Harbor Press, Cold Spring Harbor, NY, 1985.
Krimpenfort et al., “Generation of Transgenic Diary Cattle Using ‘In Vitro’ Embryo Production,” Bio/Technology 9:86, 1991.
Lazar et al., “Transforming Growth Factor alpha: Mutation of Aspartic Acid 47 and Leucine 48 Results in Different Biological Activities,” Molecular and Cellular Biology 8:1247-1252.
Liang et al., “Differential Display of Eukaryotic Messenger RNA by Means of the Plymerase Chain Reaction,” Science, vol. 257, Aug. 14, 1992, 967-971.
Lo, “Transformation by Iontophoretic Microinjection of DNA: Multiple Integrations Without Tandem Insertions,” Mol. Cell. Biol., 3:1803, 1983.
Milstein and Kohler, “Continuous cultures of fused cells secreting antibody of predefined specificity,” Nature, 256:495-97, 1975.
Nakanishi T. et al., “Cloning of a mRNA Preferentially Expressed in Chondrocytes by Differential Display . . . ,” Biochenical and Biophysical Res. Commun. 234, 206-210 (1997).
Palmiter et al., “Transgenic Mice” Cell, 41:343, 1985.
Purcel et al., “Genetic Engineering of Livestock,” Science, 244:1281, 1986.
Rosier et al., “P-Glycoprotein Expression in Cartilaginous Tumors,” Journal of Surgical Oncology, 1997; 65:95-105.
Sullivan et al., “Development og Ribozymes for Gene Therapy,” 1994, J. Invest. Derm., 103:85S-89S.
Tao et al., “Studies of Aglycosylated Chimeric Mouse-Human 1gG,” The Journal of Immunology, 143:2595-2601.
Thompson et al., “Germ Line Transmission and Expression of a Corrected HPRT Gene Product by Gene targeting in Embryonic Stem Cells,” Cell, 56:313, 1989.
Van der Putten et al., “Efficient insertion of genes into mouse germ line via retroviral vectors,” Proc. Natl. Acad. Sci. USA 82:6148, 1985.
Ausubel et al., Current Protocols in Molecular Biology, 2 (1990).
Castresana et al., “Amplification of the c-myc Proto-oncogene in Human Chondrosarcoma”,Diag. Mol. Path., 1(4): 235-38 (1992).
Clark et al., “Fusion of the EWC Gene to CHN, a Member of the Steroid/Thyroid Receptor Gene Superfamily, in a Human Myxoid Chondrosarcoma”,Oncogene, 12(2): 229-35 (1996).
Czubayko et al., “Ribozyme-targeting Elucidates a Direct Role of Pleiotrophin in Tumor Growth”,J. Biol. Chem., 269(33): 21358-63 (1994).
Dobashi et al., “Possible Association of p53 Overexpression and Mutation with High-Grade Chondrosarcoma”,Diag. Mol. Path., 2(4): 257-63 (1993).
Kraemer et al., “Gene Transfer into Pronuclei of Cattle and Sheep Zygotes”,Banbury Report 20, Cold Spring Harbor Press, Cold Spring Harbor, NY, pp. 221-227 (1985).
Köhler et al., “Continuous Cultures of Fused Cells Secreting Antibody of Predefined Specificity”,Nature, 256:495-97 (1975).
Mahieu et al., “Construction of a Ribozyme Directed Against Human Interleukin-6 mRNA: Evaluation of Its Catalytic Activity In Vitro and In Vivo”,Blood, 84(11) 3758-65 (1994).
Reid, “New Developments in the Diagnosis of Chondrosaracoma”,J. Path., 163:93-94 (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chondrosarcoma associated genes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chondrosarcoma associated genes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chondrosarcoma associated genes will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3750506

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.