Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-08-04
1993-12-14
Wityshyn, Michael G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530350, 530399, A61K 3702, C07K 704
Patent
active
052703037
ABSTRACT:
A novel chondromodulin-II protein having a molecular weight of about 16,000 dalton on SDS-PAGE, capable of stimulating the growth of chondrocytes with or without fibroblast growth factor and promoting the differential potency of said cells, and a pharmaceutical composition containing said protein as an active ingredient.
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patent: 5106626 (1992-04-01), Parsons et al.
The Journal of Biological Chemistry vol. 265 No. 17, Jun. 15, 1990 pp. 9628-9633, "An 18-kDa Glycoprotein from Bovine Nasal Cartilage" Neame et al.
Biochemical and Biophysical Research Communications vol. 175, No. 3, Mar. 29, 1991 "Molecular Cloning of a New Class of Cartilage-Specific Matrix, Chondromodulin-I, Which Stimulates Growth of Cultured Chondrocytes" Hiraki et al. pp. 971-977.
Cell vol. 59, 1115-1125, Dec. 22, 1989 "The v-myb Oncogene Product Binds to and Activates the Promyelocyte-Specific mim-1 Gene" Ness et al.
Hiraki Yuji
Kamizono Akihito
Kondo Jun
Suzuki Fujio
Tanaka Hideho
Mitsubishi Kasei Corporation
Sayala C.
Wityshyn Michael G.
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