Chondroitin synthase and nucleic acid encoding the enzyme

Details Chondroitin synthase and nucleic acid encoding the enzyme Chondroitin synthase and nucleic acid encoding the enzyme

2007-06-19

2007-06-19

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C435S084000, C435S069100

Reexamination Certificate

active

10516100

ABSTRACT:
A human-derived novel chondroitin synthase, which is an enzyme for synthesizing a fundamental backbone of chondroitin and has both glucuronic acid transferring activity and N-acetylgalactosamine transferring activity.

REFERENCES:
patent: 2003/0104601 (2003-06-01), DeAngelis
patent: 2003-199583 (2003-07-01), None
Hiroshi et al. ( JBC, 2001, 276, pp. 38721-38726).
Kamakari et al. (Gene bank Acession No. AJ504664, Feb. 17, 2003).
Kitagawa H. et al, “Characterization of serum bata-glucuronylt-ransferase involved in chondroitin sulfate biosynthesis” Glycobiology 1997 vol. 7 No. 7, pp. 905-911.
Rohmann K. et al, “Two N-acetylgalacto-saminyltransferase are involved in the biosynthesis of chondroitin sulfate” Eur. J. Biochem, 1985, vol. 148 No. 3, pp. 463-469.
XP-002333486, “Homo sapienschromosome 5 clone CTB-140F24, Working Draft Sequence, 5 unordered pieces” (abstract).
XP-002333487, “Human chondroitin synthetase protein SEQ ID No. 2” (abstract).
Supplementary Partial European Search Report dated Jul. 12, 2005.

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