Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Reexamination Certificate
2011-03-01
2011-03-01
Bertoglio, Valarie (Department: 1632)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
C435S069100, C435S070100, C435S395000, C424S093210, C424S093200
Reexamination Certificate
active
07897384
ABSTRACT:
Methods and compositions for producing therapeutic agents using chondrocytes are provided. The genetically engineered chondrocytes can be used to express the therapeutic agent in a subject, including in an environment typically associated with chondrocytes and in an environment not typically associated with chondrocytes.
REFERENCES:
patent: 4105034 (1978-08-01), Shalaby et al.
patent: 4130639 (1978-12-01), Shalaby et al.
patent: 4140678 (1979-02-01), Shalaby et al.
patent: 4141087 (1979-02-01), Shalaby et al.
patent: 4205399 (1980-06-01), Shalaby et al.
patent: 4208511 (1980-06-01), Shalaby et al.
patent: 4332255 (1982-06-01), Hakim et al.
patent: 4352883 (1982-10-01), Lim
patent: 4373527 (1983-02-01), Fischell
patent: 4387715 (1983-06-01), Hakim et al.
patent: 4551128 (1985-11-01), Hakim et al.
patent: 4595390 (1986-06-01), Hakim et al.
patent: 4615691 (1986-10-01), Hakim et al.
patent: 4642120 (1987-02-01), Nevo et al.
patent: 4904259 (1990-02-01), Itay
patent: 5041138 (1991-08-01), Vacanti et al.
patent: 5053050 (1991-10-01), Itay
patent: 5108753 (1992-04-01), Kuberasampath et al.
patent: 5283187 (1994-02-01), Aebischer et al.
patent: 5464929 (1995-11-01), Bezwada et al.
patent: 5468253 (1995-11-01), Bezwada et al.
patent: 5554148 (1996-09-01), Aebischer et al.
patent: 5595751 (1997-01-01), Bezwada et al.
patent: 5597579 (1997-01-01), Bezwada et al.
patent: 5607687 (1997-03-01), Bezwada et al.
patent: 5618552 (1997-04-01), Bezwada et al.
patent: 5620698 (1997-04-01), Bezwada et al.
patent: 5645850 (1997-07-01), Bezwada et al.
patent: 5648088 (1997-07-01), Bezwada et al.
patent: 5698213 (1997-12-01), Jamiolkowski et al.
patent: 5700583 (1997-12-01), Jamiolkowski et al.
patent: 5842477 (1998-12-01), Naughton et al.
patent: 5855619 (1999-01-01), Caplan et al.
patent: 5859150 (1999-01-01), Jamiolkowski et al.
patent: 5869041 (1999-02-01), Vandenburgh
patent: 5872094 (1999-02-01), Goetinck et al.
patent: 5902745 (1999-05-01), Butler et al.
patent: 5939323 (1999-08-01), Valentini et al.
patent: 5968502 (1999-10-01), Treco et al.
patent: 5980508 (1999-11-01), Cardamone et al.
patent: 6001352 (1999-12-01), Boyan et al.
patent: 6008013 (1999-12-01), Reynolds
patent: 6013853 (2000-01-01), Athanasiou et al.
patent: 6048729 (2000-04-01), Selden et al.
patent: 6054288 (2000-04-01), Selden et al.
patent: 6103528 (2000-08-01), An et al.
patent: 6149902 (2000-11-01), Artavanis-Tsakonas et al.
patent: 6165225 (2000-12-01), Antanavich et al.
patent: 6224893 (2001-05-01), Langer et al.
patent: 6261584 (2001-07-01), Peery et al.
patent: 6303379 (2001-10-01), Selden et al.
patent: 6306169 (2001-10-01), Lee et al.
patent: 6361771 (2002-03-01), Tao et al.
patent: 6365149 (2002-04-01), Vyakarnam et al.
patent: 6387693 (2002-05-01), Rieser et al.
patent: 6395292 (2002-05-01), Peery et al.
patent: 6410313 (2002-06-01), Kasahara et al.
patent: 6413511 (2002-07-01), Glorioso et al.
patent: 6455304 (2002-09-01), Weigel et al.
patent: 6458889 (2002-10-01), Trollsas et al.
patent: 6472181 (2002-10-01), Mineau-Hanschke
patent: 6548249 (2003-04-01), Anderson et al.
patent: 6635268 (2003-10-01), Peery et al.
patent: 7149587 (2006-12-01), Wardle et al.
patent: 2001/0002392 (2001-05-01), Heinegard et al.
patent: 2001/0014475 (2001-08-01), Frondoza et al.
patent: 2001/0033857 (2001-10-01), Vyakarnam et al.
patent: 2001/0037017 (2001-11-01), Luyten et al.
patent: 2001/0051834 (2001-12-01), Frondoza et al.
patent: 2002/0003727 (2002-01-01), Hartmann
patent: 2002/0006428 (2002-01-01), Mahmood et al.
patent: 2002/0009477 (2002-01-01), Mahmood et al.
patent: 2002/0037279 (2002-03-01), Vandenburgh
patent: 2002/0076810 (2002-06-01), Radice et al.
patent: 2002/0094569 (2002-07-01), Yu et al.
patent: 2002/0110544 (2002-08-01), Goldberg et al.
patent: 2002/0115218 (2002-08-01), Havenga et al.
patent: 2002/0142984 (2002-10-01), Brigham et al.
patent: 2002/0160471 (2002-10-01), Kisiday et al.
patent: 2002/0177224 (2002-11-01), Madry et al.
patent: 2003/0012805 (2003-01-01), Chen et al.
patent: 2003/0036523 (2003-02-01), Czichos et al.
patent: 2003/0064088 (2003-04-01), Carvalho et al.
patent: 2003/0077260 (2003-04-01), Mineau-Hanschke
patent: 2003/0167054 (2003-09-01), Rosenberg et al.
patent: 2005/0054595 (2005-03-01), Binette et al.
patent: 2005/0191301 (2005-09-01), Heavner et al.
patent: 2006/0292131 (2006-12-01), Binette et al.
patent: 62198388 (1987-09-01), None
patent: 62269697 (1987-11-01), None
patent: 2002524083 (2002-08-01), None
patent: WO 96/34955 (1996-11-01), None
patent: WO 96/39196 (1996-12-01), None
patent: WO 99/11789 (1999-03-01), None
patent: 0014261 (2000-03-01), None
patent: WO 02/074912 (2002-09-01), None
patent: WO 03/082302 (2003-10-01), None
Okada et al (Biol. Pharm. Bull. 1997. vol. 20, No. 3, pp. 255-258).
Grogan, et al., “Engineering Cartilage for Drug Delivery,” Institute of Pathology, University of Bern, Murtenstrasse 31, 3010, Bern Switzerland.
Manry, et al., “Efficient lipid-mediated gene transfer to articular chondrocytes,” Gene Therapy, vol. 7, No. 4, pp. 286-291, Feb. 2002.
Himeno, et al., “Impaired Vascular Invasion of CBFA1-Deficient Cartilage Engrafted in the Spleen,” Journal of Bone and Mineral Research, vol. 17, No. 7, pp. 1297-1305, Jul. 2002.
Arai, et al. “Adenovirus Vector-Mediated Gene Transduction to Chondrocytes: In Vitro Evaluation of Therapeutic Efficacy of Transforming Growth Factor-Beta1 and Heat Shock Protein 70 Gene Transduction,” Journal of Rheumatology, vol. 24, pp. 1787-1795, 1997.
Bartholomew, et al., “Baboon mesencymal stem cells can be genetically modified to secrete hum erythropoietin in vovi,”, Human Gene Therapy, vol. 12, No. 12, pp. 1527-1541, Aug 2001.
Smith et. al., (1993) Neuroscience 52: 7-16.
Golab et. al., (1998) Ann. Oncol., 9: 63-69.
Suda, (1985) Calcif Tissue Int., 37: 82-90.
Sullivan et al., (1994) J. Biol. Chem., 269: 22500-22506.
Takaori-Kondo et al., (1998) Blood, 91: 4747.
Uludag et al. (Advanced Drug Delivery Reviews. 2000; 42: 29-64).
Wong et. al., (1999) Curr. Opin. Immunol., 11: 643-647.
Zamir et. al., (1984) Brain Res., 322: 356-360.
International Search Report and Written Opinion of PCT/US2008/064481 dated Sep. 23, 2008.
Leboy et. al., (1994) Microscopy Res. and Technique 28: 483-491.
Steinert et al. “Arthritis Research & Therapy,” 2007, vol. 9. No. 213, pp. 1-15.
Weitzman, Annu. Rev. Biochem, 2005, vol. 74, pp. 711-738.
Farnum C E, Lee R, O'Hara K, Urban J P G; volume increase in growth plate chondrocytes during hypertrophy: the contribution of organic osmolytes. Bone 2002;30(4):574-81.
Anderson et. al., (1990) Cancer Res., 50: 1853.
Baekkeskov et. al., (1990) Nature, 151-156.
Bakay et. al., (1985) Appl. Neurophysiol., 48: 358-361.
Baskin et. al., (1994) Life Sci. 54: 471-479.
Bjorklund et. al., (1982) Nature 298: 652-654.
Bohme et. al., (1992) Prog. Growth Factor res., 4: 45-68.
Bohme et. al., (1995)Exp. Cell Res., 216:191-198.
Bookman et. al., (1998) Semin. Oncoi., 25:381-396.
Carelli (1982) Proc. Natl. Acad. Sci., USA 79: 5392-5395.
Carson et. al., (1998) J. Surg. Res., 75: 97.
Castano et. al., (1991) J. Clin. Endocr. Metab., 73: 1197-1201.
Corvol et al., (1980) FEBS Lett., 116: 273-276.
Crabb et. al., (1990) J. Bone Mineral Res., 5: 1105-1112.
Dotta et al., (1992) Endocrinology 130: 37-42.
Downie et. al., (1994) Dev. Biol., 162: 195.
Fueshko et. al., (1994) Dev. Biol., 166: 331-348.
Gelb et. al., (1990) Endocrinology, 127: 1941-1947.
Gerstenfeld et. al., (1990) Conn. Tiss. Res. 24: 29-39.
Gillard et. al., (1989) Journal Immunol. Methods., 142: 3826-3832.
Greiss et. al., (1993) Biophysical J., 65: 138-148.
Griscelli et al., (1998) proc. Natl. Acad. Sci., USA 95: 6367.
Hahn et al., (1984) Endocr. Res., 10: 123-138.
Hamamori et. al., (1995) J. Clinical Investigation, 95: 1808-1813.
Hantraye et. al., (1990) Exp. Neurol., 108: 91-1014.
Hantraye et. al., (1992) Proc. Natl. Acad. Sci., USA 89: 4187-4191.
Hearing et al., (1986) J. Immunol., 137: 379.
Isacson et. al., (1985) Neuroscience 16: 799-817.
Isacson et. al., (1989) Exp. Brain Res., 75(1): 213-220
Binette Francois
Story Brooks J.
Bertoglio Valarie
Ethicon Inc.
LandOfFree
Chondrocyte therapeutic delivery system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chondrocyte therapeutic delivery system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chondrocyte therapeutic delivery system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2749993