Cholinergic compositions and uses thereof

Details Cholinergic compositions and uses thereof Cholinergic compositions and uses thereof

1997-11-26

1999-11-02

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514560, 514552, A61K 3123

Patent

active

059771747

ABSTRACT:
The invention provides compositions that include conjugates of a cholinergic agent and a fatty acid, preferably cis-docosahexaenoic acid. The conjugates are useful in treating disorders resulting from cerebral ischemia including stroke.

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Related PCT Search Report--PCT/US98/24490.
Nishio, K. et al., DHA-Vc, DHA-cho, and PC Metabolism: 200-208 (1993).
Schabitz WR, et al., "The Effects of Prolonged Treatment with Citicoline in Temporary Experimental Focal Ischemia", J Neurol Sci, 1996, 138(1-2): 21-25. (Abstract).
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