Choline salicylate compositions and methods for achieving analge

Details Choline salicylate compositions and methods for achieving analge Choline salicylate compositions and methods for achieving analge

1975-05-12

1976-06-22

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

A61K 31695

Patent

active

039652637

ABSTRACT:
Choline salicylate-silanized silicon dioxide a stable solid, non-hygroscopic composition possessing the full spectrum of analgesic, anti-pyretic and anti-inflammatory properties of choline salicylate is prepared by reaching a choline ion with a salicylate ion and then combining with silanized silicon dioxide in the presence of an inert anhydrous solvent to form the new composition. Solid pharmaceutical dosage forms are prepared with the new composition which are useful in the treatment of musculo-skeletal disease, the relief of pain and the lowering of fever in humans and animals. A method for increasing the concentration of blood salicylate ion through the oral administration of the aforesaid choline salicylate-silanized silicon dioxide and pharmaceutical composition containing the same, is presented.

REFERENCES:
chem. Abst., vol. 59, 11529a, (1963).
Chem. Abst., vol. 73, 20898j, (1970).

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