Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Gas produced in situ by chemical reaction
Patent
1978-03-09
1979-10-23
Fagelson, Anna P.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Gas produced in situ by chemical reaction
424 34, 424 35, 424 43, 424 78, 424 79, A61K 946, A61K 3174, A61K 4700
Patent
active
041721209
ABSTRACT:
A solid pharmaceutical composition comprising anhydrous cholestyramine, 0.6 to 1.7 parts by weight of low viscosity grade alginic acid/sodium alginate per weight of cholestyramine, the low viscosity grade alginic acid/sodium alginate having 0 to 75% of the acid groups neutralized, 0.1 to 0.3 parts by weight of citric acid per weight of sodium alginate, and sufficient sodium carbonate or bicarbonate mixtures thereof to neutralize the acid groups of the alginic and citric acids. The compositions may be used in the treatment of conditions associated with duodeno-gastric reflux of bile into the stomach.
REFERENCES:
patent: 3369944 (1968-02-01), Sandmark
patent: 3499960 (1970-02-01), Macek
patent: 3769399 (1973-10-01), Hagerman
patent: 3974272 (1976-08-01), Polli
patent: 4079125 (1978-03-01), Sipos
Martindale, Extra Pharm., Pharm. Press, London, 26th ed., pp. 127 and 2050.
Whistler, Industrial Gums, Acd. Press, N. Y., 1959, pp. 68-69.
Fryers Gordon R.
Todd Richard S.
Fagelson Anna P.
Reckitt & Colman Products Limited
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