Cholesteryl modified oligonucleotides

Details Cholesteryl modified oligonucleotides Cholesteryl modified oligonucleotides

1989-06-06

1990-09-18

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 5, 536 28, 536 29, C07H 2100

Patent

active

049580132

ABSTRACT:
Oligonucleotides modified at their backbones by the attachment of cholesteryl are described. The modified oligonucleotides anchor in the cell membrane to serve as a probe and to provide therapeutic activity.

REFERENCES:
patent: 4283394 (1981-08-01), West et al.
patent: 4458066 (1984-07-01), Caruthers et al.
patent: 4728730 (1988-03-01), Frey et al.

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