Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1982-12-03
1984-06-05
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 22, 424 28, 424 14, 424177, 424178, 424179, 424 95, A61K 926, A61K 3156, A61K 3702, A61K 3726
Patent
active
044527756
ABSTRACT:
Delivery systems for releasing macromolecular active agents to a body site at a controlled rate for a prolonged period of time, comprising a cholesteric matrix permeable to passage of the macromolecular active agent by diffusion, are disclosed. The cholesteric matrix comprises cholesterol powder and cholesterol prills optionally in combination with a binding agent and a lubricating agent. The macromolecular active agent is dispersed throughout the matrix; macromolecules suitable for release from this delivery system have molecular weights of about 1300 to about 75,000 and are at least very slightly soluble in water.
REFERENCES:
patent: 3800038 (1974-03-01), Rudel
patent: 3828106 (1974-08-01), Rudel
patent: 4164560 (1979-08-01), Folkman et al.
patent: 4180560 (1979-12-01), Katz et al.
patent: 4244949 (1981-01-01), Gupta
Rudel C.A. 81 #29537p, (1974).
Joseph et al., C.A. 87 #141179y, (1977).
Misra C.A. 89 #135762h, (1978).
Beck et al., C.A. 90 #92364f, (1979).
Meyer et al., C.A. 91 #49927a, (1977).
Gupta C.A. 91 #128998n, (1979).
Gupta C.A. 94 #115055e, (1981).
Misra et al., C.A. 95 #192314m, (1981).
Bernabei C.A. 97 #150631y, (1982).
Pontani C.A. 98 #166811p, (1983).
Buckles Ellen J.
Krubiner Alan M.
Moran Tom M.
Rose Shep K.
Syntex (U.S.A.) Inc.
LandOfFree
Cholesterol matrix delivery system for sustained release of macr does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cholesterol matrix delivery system for sustained release of macr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cholesterol matrix delivery system for sustained release of macr will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1496910