Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-11-24
1994-05-31
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31335
Patent
active
053170318
ABSTRACT:
Cholesterol lowering compounds and compositions are formed from the photochemical treatment of the Zaragozic Acids followed by esterification. These compounds and compositions are active squalene synthetase inhibitors useful in the treatment of hypercholesterolemia.
REFERENCES:
patent: 5096923 (1992-03-01), Bergstrom et al.
patent: 5102907 (1992-04-01), Bergstrom et al.
Arison Byron H.
Doss George A.
MacConnell John G.
Monaghan Richard L.
Dolan Catherine A.
Jordan Kimberly R.
Matukaitis Paul D.
Merck & Co. , Inc.
Meredith Roy D.
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