Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof
Patent
1976-09-17
1977-10-11
Jaisle, Cecilia M. S.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Allergen or component thereof
424283, 260327TH, 2603452, C07D31104, A61K 3138
Patent
active
040536262
ABSTRACT:
Phenoxyacetic acids of the formula ##STR1## wherein R.sub.1 is H or alkyl of 1-4 carbon atoms; R.sub.2 is H, or when R.sub.4 is Q, also alkyl of 1-4 carbon atoms; R.sub.3 is methyl, phenyl or chlorophenyl; and R.sub.4 is piperidino, isoindolino, 1,2,3,4-tetrahydroquinolino, 1-R.sub.5 -1,2,3,4-tetrahydro-4-quinolyl, 4-piperidinophenyl, 4-piperidinophenoxy, 1-pyrryl, or Q, wherein R.sub.5 is H or alkyl of 1-4 carbon atoms; and Q is 4-oxo-1,2,3,4-tetrahydroquinolino, 4-hydroxy-1,2,3,4-tetrahydroquinolino, 4-chromanyl, 4-thiochromanyl or 1-phenyl-1,2,3,4-tetrahydro-4-quinolyl; and the salts thereof, possess cholesterol level-lowering activity.
REFERENCES:
patent: 3471520 (1969-10-01), Irmscher et al.
patent: 3535344 (1970-10-01), Irmscher et al.
Kayser Detlev
Mehrhof Werner
Nowak Herbert
Schacht Erich
Simane Zdenek
Jaisle Cecilia M. S.
Merck Patent Gesellschaft mit beschrankter Haftung
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