Cholera vaccines and peptides

Details Cholera vaccines and peptides Cholera vaccines and peptides

1988-04-29

1992-03-24

Moskowitz, Margaret

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530825, 514 12, 424 92, C07K 1300, C07K 1500, A61K 3702

Patent

active

050989987

ABSTRACT:
The gene encoding the TcpA pilus has been cloned. It encodes a protein useful in live, killed-cell, and synthetic vaccines. Protein production is enhanced by specific medium conditions.

REFERENCES:
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Yamamoto, T. et al., 1987, J. Bacteriol., 169(3): 1352-7, Evolutionary Origin . . . , 1987 abstract only.
Ehara, M. et al., Trop. Med. 28(1):21-34. 1986, Fibrige of Vitrio Cholerae 0-1 . . . , abstract only.
Taylor et al., Proc. Natl. Acad. Sci. U.S.A. 84:2833, May 1987.
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Taylor et al., Biol. Abstr. 84(4): AB-443, Genetics of Bacteria and Viruses.

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