Cholecystokinin antagonists useful for treating depression

Details Cholecystokinin antagonists useful for treating depression Cholecystokinin antagonists useful for treating depression

1991-08-20

1992-10-06

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514 80, 5142375, 514330, 514404, 514563, A61K 3155, A61K 31675, A61K 31535, A61K 3144

Patent

active

051531917

ABSTRACT:
The invention concerns cholecystokinin antagonists useful in the treatment major and minor forms of depression. Especially useful are CCK.sub.A antagonists such as devazepide and CCK.sub.B antagonists such as L-365,260 and LY262691.

REFERENCES:
patent: 4791215 (1988-12-01), Rovati et al.
patent: 4820834 (1989-04-01), Evans et al.
The Merck Manual, 14th ed. (1982) pp. 1448-1462.
Ann. Rev. Pharmacol. Toxicol., 1991, 31: 469-501, G. N. Woodruff et al., "Cholecystokinin Antagonists".
J. Med. Chem., 1991, 34, 1505-1508, M. J. Yu et al., "Quinazolinone Cholecystokinin-B Receptor Ligands".

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