Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1983-07-01
1985-07-23
Bond, Robert T.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
435119, 435913, C07D51900, A61K 3155, C12P 1718, C12R 166
Patent
active
045307903
ABSTRACT:
The compound having Formula I and several minor related compounds are produced by the aerobic fermentation of Aspergillus alliaceus Thom and Church, ATCC No. 20655 or ATCC No. 20656. ##STR1## The compound of Formula I and the several minor related compounds are antagonists of cholecystokinin (CCK). CCK antagonists are useful in the treatment and prevention of disorders of the gastrointestinal, central nervous and appetite regulatory systems of animals, especially humans.
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Chang Raymond S. L.
Goetz Michael A.
Monaghan Richard L.
Bond Robert T.
Linek Ernest V.
Lopez Gabriel
Merck & Co. , Inc.
Szura Daniel T.
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