Chlortetracycline compositions

Details Chlortetracycline compositions Chlortetracycline compositions

1976-12-07

1978-03-28

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

424227, A61K 3179, A61K 3165

Patent

active

040815277

ABSTRACT:
Aqueous solutions of chlortetracycline or salts thereof, a pharmaceutically acceptable calcium compound and 2-pyrrolidone as a co-solvent, said solution having a pH of 8 to 10 and being useful as an injectable composition combining low viscosity, high potency, good clarity and good stability.

REFERENCES:
patent: 2987437 (1961-06-01), Hessel
patent: 3062717 (1962-11-01), Hammer
patent: 3932653 (1976-01-01), Stoughton
patent: 3957994 (1976-05-01), Schroer
patent: 3969516 (1976-07-01), Stoughton
Japanese Patent Appln. Publicat. No. Sho 47-303 (Jan. 6, 1972).
Japanese Patent Appln. Publicat. No. Sho 43-1758 (Jan. 22, 1968).
Gans & Higuchi - J. Pharm. Sci., vol. 46, (1957) p. 458.

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