Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-12-01
1986-07-08
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546180, A61K 3147, C07D21512
Patent
active
045993459
ABSTRACT:
A chlorinated quinoline derivative of formula (I) ##STR1## wherein R.sup.1 is --CCl.sub.3, --CF.sub.3, --CHCl.sub.2 or --CH.sub.2 Cl, R.sup.2 is hydrogen when R.sup.3 is not hydrogen, or is halogen, C.sub.1-4 alkoxy, C.sub.1-4 alkyl or R.sup.1, R.sup.3 is hydrogen when R.sup.2 is not hydrogen or is halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or CF.sub.3, R.sup.6 is hydrogen or halogen, X is halogen. The compounds are made by chlorination of selected compounds as disclosed and the new compounds can have antimicrobial, antifungal or analgesic effects.
REFERENCES:
patent: 4277607 (1981-07-01), Bulidon et al.
Kato et al., Chem. Ph. Bull., 29, 1069-1075, 1969.
Imre nee Virag Ilona
Salamon Zoltan
Sebestyen Magdolna
Alkaloide Vegyeszeti Gyar
Dubno Herbert
Hollrah Glennon H.
Ross Karl F.
Springer D. B.
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