Chlorofluorocarbon-free mometasone furoate aerosol formulations

Details Chlorofluorocarbon-free mometasone furoate aerosol formulations Chlorofluorocarbon-free mometasone furoate aerosol formulations

1997-08-27

2000-05-30

Bawa, Raj

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 46, A61K 912

Patent

active

060688327

ABSTRACT:
The invention relates to suspension aerosol formulations which exhibit stable particle sizes, containing mometasone furoate, about 1 to about 10 weight percent ethanol and 1,1,1,2,3,3,3-Heptafluoropropane as the propellant. A surfactant, such as oleic acid, can also be included. These formulations are suitable for use in metered dose inhalers.

REFERENCES:
patent: 5118494 (1992-06-01), Schultz et al.
patent: 5225183 (1993-07-01), Purewal et al.
patent: 5474759 (1995-12-01), Fassberg et al.
patent: 5653962 (1997-08-01), Akehurst et al.
patent: 5658549 (1997-08-01), Akehurst et al.
patent: 5674471 (1997-10-01), Akehurst et al.

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