Chlorocitric acids

Details Chlorocitric acids Chlorocitric acids

1978-12-26

1982-01-26

Love, Ethel G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

2603439, 26034862, 562584, A61K 3119, C07C 59265

Patent

active

043128858

ABSTRACT:
The present invention relates to chlorocitric acids of the formula ##STR1## and stereoisomers, optical antipodes and pharmaceutically acceptable salts thereof, to methods of preparation thereof, including intermediates involved therein, and to their use as anorectic agents for the treatment of obesity in mammals.

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patent: 3356721 (1967-12-01), Wiley
patent: 3536630 (1970-10-01), Mehltretter
patent: 3764692 (1973-10-01), Lowenstein
patent: 3901915 (1975-08-01), Perry et al.
patent: 3960933 (1976-06-01), Guthrie et al.
patent: 4123458 (1978-10-01), Gutierrez et al.
Pawolleck, Justus Liebigs Ann., 178, 150 (1875).
Martins et al., Hoppe Seyler's Zeitschrift Physiol. Chem. 269, 23 (1941).
Chem. Abstracts 1967-1971, Collective Index, p. 7536S.
Chem. Abstracts 1917-1926, Collective Index, p. 3442.
Chem. Abstracts 87:95821b.
Chem. Abstracts 55:13484a.
Sullivan et al., Am. J. Clin. Nutri, 30, 767 (1977).
Research Communications in Chemical Pathology and Pharmacology, vol. 18, No. 1, Sep. 1977, pp. 83-94.

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