Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1979-01-25
1980-07-22
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
562468, 560 58, C07C 6976
Patent
active
042140951
ABSTRACT:
Novel compounds of the formula (1) ##STR1## wherein R.sup.1 and R.sup.2 are different lower alkyls and R.sup.3 is a lower alkyl or a methyl pyridine group, and the acid addition salts of formula (1) compounds when R.sup.3 is methyl pyridine. The novel compounds have an asymmetric C-atom and may be in the form of the D,L racemates or the D or L stereoisomers.
These compounds are useful in the treatment of hypercholesterolemia and hyperlipidemia because of their high effectiveness in reducing the level of cholesterol and lipids in the blood combined with very low general toxicities and substantially reduced hepatomegalitic effects.
REFERENCES:
patent: 4072754 (1978-02-01), Schacht et al.
Adrian Rudolf
Ahmed Quazi
Jahn Ulrich
Thiele Kurt
Killos Paul J.
Kleeman Werner W.
Siegfried Aktiengesellschaft
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