Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines

Details Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines

1981-04-13

1982-09-28

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23995

Patent

active

043519407

ABSTRACT:
2,4-Diaminoquinazolines of the formula ##STR1## wherein Y.sup.1 is hydrogen or chloro, Y.sup.2 is OR, Y.sup.3 is hydrogen or OR such that when Y.sup.1 is hydrogen, Y.sup.3 is OR and when Y.sup.1 is chloro, Y.sup.3 is hydrogen or OR, and the pharmaceutically acceptable salts thereof; R represents an alkyl group having from one to three carbon atoms;

REFERENCES:
patent: 3511836 (1970-05-01), Hess
patent: 3669968 (1972-06-01), Hess
patent: 3920636 (1975-11-01), Takahashi et al.
patent: 4001237 (1977-01-01), Partyka et al.
patent: 4001238 (1977-01-01), Partyka et al.
patent: 4026894 (1977-05-01), Winn et al.
patent: 4060615 (1977-11-01), Matier et al.
patent: 4101548 (1978-07-01), Crenshaw et al.
Althuis et al., J. Med. Chem., 20, 146-149 (1977).

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