Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Peroxide or compositions of or releasing gaseous oxygen or...
Reexamination Certificate
2006-12-21
2011-11-29
Krass, Frederick (Department: 1612)
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Peroxide or compositions of or releasing gaseous oxygen or...
C424S488000, C424S665000, C424S613000, C514S275000
Reexamination Certificate
active
08067035
ABSTRACT:
Described herein are chlorite formulations having a pH between about 7 and about 8.5, wherein the chlorite formulations are substantially free of deleterious non-chlorite components. Described herein are chlorite formulations, including pharmaceutical formulations, which are formulated for systemic, parenteral, or intravenous administration. Described herein are methods of preparing and methods of using the chlorite formulations described herein.
REFERENCES:
patent: 2169066 (1939-08-01), Cunningham
patent: 4507285 (1985-03-01), Kuhne
patent: 4725437 (1988-02-01), Kuhne
patent: 5503847 (1996-04-01), Queen et al.
patent: 5622725 (1997-04-01), Kross
patent: 5639295 (1997-06-01), Wellinghoff et al.
patent: 5723095 (1998-03-01), Fricker et al.
patent: 5782992 (1998-07-01), Frangione
patent: 5830511 (1998-11-01), Mullerate et al.
patent: 5855922 (1999-01-01), Danner et al.
patent: 5877222 (1999-03-01), McGrath
patent: 6086922 (2000-07-01), Kuhne
patent: 6132702 (2000-10-01), Witt et al.
patent: 6488965 (2002-12-01), Karageozian
patent: 6703202 (2004-03-01), McGrath et al.
patent: 6706256 (2004-03-01), Lawlor
patent: 2005/0181068 (2005-08-01), McGrath
patent: 327132 (1972-01-01), None
patent: WO 99/17787 (1999-04-01), None
patent: WO 03/048773 (2003-06-01), None
patent: WO 2005/076819 (2005-08-01), None
Moore, David D, Current Protocols in Molecular Biology, 1996-2000, John Wiley and Sons, Inc, Appendix 2, A.2.1 A.2.7.
American Regent, “Sodium Phosphate for Injection—Product Prescribing Information” IN3405. Published online: Jul. 10, 2005.
Inorganic Ventures Certificate of Analysis—I-Cal Ion Chromatography Solution—Catalog No. ICCLO21-1; ICCLO21-5. Available at http://www.ivstandards.com/CoA/ICCLO21.pdf. Accessed Dec. 22, 2006.
Inorganic Ventures Material Safety Data Sheet—ICCLO21-1; ICCLO21-5. Dated Jul. 19, 2004. Available at http://inorganicventures.thewercselite.com/docs/ICCLO21—English,%20USA.pdf.
McGrath, et al. Development of WF10, a novel macrophage-regulating agent. Curr Opin Investig Drugs. 2002; 3(3):365-73.
Product Insert: Data and instructions for the Use of IMMUNOKINE® WF10 (TCDO) I.v. Solution for Intravenous Infusion. OXO Chemie. Published approximately 1997.
Qian, et al. A clean production process of sodium chlorite from sodium chlorate. Chemical Engineering Shool. South China University of Technology. Editor(s): Liu, Huanbin; Zhan, Huaiyu; Xie, Yimin. Emerging Technologies of Pulping & Papermaking, Proceedings of the International Symposium on Emerging Technologies of Pulping & Papermaking, 2nd, Guangzhou, China, Oct. 9-11, 2002: 464-471. Publisher: South China University of Technology Press, Guangzhou, China. (Pre-publication copy provided; 9 pages).
CAMEO Chemicals. Sodium chlorite. Available at http://cameochemicals.noaa.gov/chemical/1479. Accessed Jan. 12, 2009.
Inorganic Ventures Certificate of Analysis dated Sep. 4, 2008.
Le, K. Pure Chlorite Developed by IV. Available at http://www.ivstandards.com/tech/articles/technical/chlorite.asp. Accessed Jan. 13, 2009.
Nation Master. Chlorine dioxide. Available at http://www.nationmaster.com/encyclopedia/chlorine-dioxide. Accessed Jan. 12, 2009.
International search report dated Oct. 29, 2007 for PCT Application No. US06/48941.
Kempf, et al. Comparative study on the effects of chlorite oxygen reaction product TCDO (tetrachlorodecaoxygen) and sodium chlorite solution (NaClO2) with equimolar chlorite content on bone marrow and peripheral blood of BDIX rats. Drugs Exp Clin Res. 1993;19(4):165-74.
Seta S, Miyake B, Sato H, et al. 1991. Acute oral toxicity and acute irritation test to skin and eye of sodium chlorite. Kagaku Keisatsu Kenkyusho Hokoku Hokagaku Hen 44(1):7-22.
Cohen, I. K., et al., eds., Wound Healing, W. B. Saunders Co., Philadelphia, 1992, pp. 584-586.
Kurokawa, Y. et al., Cancer Lett.,“Studies on the promoting and complete carcinogenic activities of some oxidizing chemicals in skin carcinogenesis.” Oct. 1984;24(3):299-304.
United States Pharmacopeia and National Formulary (USP 32-NF 27). Chapters <71> Sterility Tests and <1211> Sterilization. Rockville, MD: United States Pharmacopeia Convention. Dec. 1, 2009.
United States Pharmacopeia and National Formulary (USP 32-NF 27). Chapter <1> Injections. Rockville, MD: United States Pharmacopeia Convention. Dec. 1, 2009.
Ercros Safety Data Sheet. Sodium Chlorite (Solution). Aug. 2009.
Accepta Material Safety Data Sheet. Sodium Chlorite. Jan. 6, 2004.
Sigma-Aldrich Safety Data Sheet. Sodium Chlorite. Mar. 13, 2010.
Science Lab.com Material Safety Data Sheet. Sodium Chlorite. Oct. 9, 2005.
ERCO Worldwide Material Safety Data Sheet. Sodium Chlorite 5%-14%. Nov. 3, 2005.
OxyChem Technical Data Sheet. Sodium Chlorite Health & Safety. Jan. 2009.
OxyChem Technical Data Sheet. Technical Sodium Chlorite (EPA Registered) for Chlorine Dioxide Generation. Jan. 2009.
Agency for Toxic Substances and Disease Registry. Public Health Statement: Chlorine Dioxide and Chlorite. Sep. 2004.
Veerasarn, et al. Reduced recurrence of late hemorrhagic radiation cystitis by WF10 therapy in cervical cancer patients: a multicenter, randomized, two-arm, open-label trial. Radiother Oncol. Nov. 2004;73(2):179-85.
Cunningham, et al. The System Sodium Chlorite-Sodium Chloride-Water at Various Temperatures. The Journal of the American Chemical Society 1955; 77(3): 799-801.
Tarimci, et al. Anhydrous Sodium Chlorite. Acta Cryst. 1976; B32: 610-612.
Azhir Arasteh Ari
Boulanger William
Krass Frederick
Neuraltus Pharmaceuticals, Inc.
Webb Walter
Wilson Sonsini Goodrich & Rosati
LandOfFree
Chlorite formulations, and methods of preparation and use... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chlorite formulations, and methods of preparation and use..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chlorite formulations, and methods of preparation and use... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4277056