Chlorine exchange for fluorine in 2-fluoropyridine compounds

Details Chlorine exchange for fluorine in 2-fluoropyridine compounds Chlorine exchange for fluorine in 2-fluoropyridine compounds

1984-11-26

1986-01-28

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21172

Patent

active

045672741

ABSTRACT:
A method of exchanging a chlorine atom for a fluorine atom at the 2-position of a 2-fluoropyridine compound which comprises contacting a 2-fluoropyridine compound with a substituted or unsubstituted trichloromethyl or dichlorofluoromethyl alpha, beta or gamma picoline compound at a temperature of 50.degree.-250.degree. C. and a pressure of atmospheric to about 100 psig.

REFERENCES:
patent: 4393214 (1983-07-01), Roberts et al.

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