Chlorination process

Details Chlorination process Chlorination process

1986-04-07

1987-06-23

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568316, C07C 4563

Patent

active

046754482

ABSTRACT:
1-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]ethanone is chlorinated to 1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]-2,2-dichloroethanone and, if desired, to 1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]-2,2,2-trichloroethanone in a solvent mixture of about 0.5-35 parts by volume of 1,2-dichloroethane and one part by volume of acetic acid. The products can then be converted to flecainide. In a preferred embodiment of the invention, the starting material is a crude, wet material that is prepared with a minimum of solids handling.

REFERENCES:
patent: 3367857 (1968-02-01), Falbe et al.
patent: 3390187 (1968-06-01), Falbe et al.
patent: 3850989 (1974-11-01), Havinga et al.
patent: 4001335 (1977-01-01), Schaffner et al.
patent: 4289909 (1981-09-01), Freenor et al.
Minakov et al., Chemical Abstracts, vol. 87, 6756z (1977).

Affiliated with

Also associated with

Rating

Chlorination process does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chlorination process, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chlorination process will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-722630