Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Reexamination Certificate
2006-08-29
2006-08-29
Jones, Dameron (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
C424S001110, C424S009100, C424S001650, C424S009300, C424S009361, C534S014000, C540S145000
Reexamination Certificate
active
07097826
ABSTRACT:
A compound comprising a chemical combination of a photodynamic tetra-pyrrolic compound with a plurality of radionuclide element atoms such that the compound may be used to enhance MR imaging and also be used as a photodynamic compound for use in photodynamic therapy to treat hyperproliferative tissue. The preferred compounds have the structural formula:where R1, R2, R2aR3, R3aR4, R5, R5aR6, R7, R7a, and R8cumulatively contain at least two functional groups that will complex or combine with an MR imaging enhancing element or ion. The compound is intended to include such complexes and combinations and includes the use of such compounds for MR imaging and photodynamic therapy treatment of tumors and other hyperproliferative tissue.
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Dougherty Thomas J.
Grossman Zachary
Kanter Peter
Pandey Ravindra K.
Dunn Michael L.
Health Research , Inc.
Jones Dameron
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