Chloride channel opener

Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

11333511

ABSTRACT:
Disclosed is a novel use of a prostaglandin compound as a chloride channel opener. According to the instant invention, chloride channels in a mammalian subject can be opened by a prostaglandin compound to facilitate chloride ion transportation.

REFERENCES:
patent: 5164415 (1992-11-01), Ueno
patent: 6015828 (2000-01-01), Cuppoletti
patent: 0310305 (1989-04-01), None
patent: 0430552 (1991-06-01), None
patent: 0690049 (1996-01-01), None
patent: 0978284 (2000-02-01), None
patent: 0979651 (2000-02-01), None
patent: 1082961 (2001-03-01), None
patent: 2075015 (1981-11-01), None
patent: 2-32055 (1990-02-01), None
patent: WO 01/70233 (2001-09-01), None
patent: WO 01/76593 (2001-10-01), None
patent: WO 02/089812 (2002-11-01), None
Database Medline ′Online! Apr. 1, 1998, Deachapunya C et al. “Regulation of chloride secretion across porcine endometrial epithelial cells by prostaglandin E2.” Database accession No. NLM9490813 XP002227298.
Hideki Sakai, et al. “A Gastric Housekeeping C1—Channel Activated via Prostaglandin EP3Receptor-mediated Ca2+/Nitric Oxide/cGMP Pathway”, Journal of Biological Chemistry, vol. 270, No. 32, Issue of Aug. 11, 1995, pp. 18781-18785. XP002227295.
Karin A. Yurko-Mauro, et al. “Prostaglandin F2astimulates CFTR activity by PKA- and PKC-dependent phosphorylation”, American Journal of Physiology -Cell Physiology, vol. 275, 1998, pp. C653-C660, XP002227296 abstract.
L.N. Chan, et al. “Activation of an Adenosine 3′,5′-Cyclic Monophosphate-Dependent C1-—Conductance in Response to Neurohormonal Stimuli in Mouse Endometrial Epithelial Cells: The Role of Cystic Fibrosis Transmembrane Conductance Regulator1”, Biology Reproduction, vol. 60, No. 2, 1999, pp. 374-380, XP002227297.
Wilfried Dalemans, et al. “Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation”, Nature, vol. 354, Dec. 19, 1991, pp. 526-528, XP000611996 ISSN: 0028-0836 abstract.
Esam Z. Dajani, et al. “Effects of E Prostaglandins, Diphenoxylate and Morphine on Intestinal Motility in Vivo”, European Journal of Pharmacology, 34 (1975) 105-113, XP001095316 ISSN: 0014-2999.
Sand et al., Journal of Endocrinology, 1995, 147:441-448.
Ueno et al., 1995, CAS:123:75627.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chloride channel opener does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chloride channel opener, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chloride channel opener will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3893996

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.