Chlorhexidine salts and compositions of same

Details Chlorhexidine salts and compositions of same Chlorhexidine salts and compositions of same

1985-05-14

1987-05-19

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514300, 514635, 26050121, 2605025R, A61K 3166, C07C 8700

Patent

active

046668969

ABSTRACT:
The dinalidixate and diphosphanilate salts of chlorhexidine possess antibacterial activity. They exhibit synergism as compared with comparable concentrations of chlorhexidine and the respective free acid. Synergistic compositions comprising a mixture of a chlorhexidine salt with phosphanilic acid or a salt of phosphanilic acid, or with nalidixic acid, or a salt of nalidixic acid are disclosed. Dermatological compositions of such novel salts, and all such mixtures, are provided.

REFERENCES:
patent: 3442938 (1969-05-01), Christensen et al.
patent: 3590036 (1971-06-01), Lesher et al.
patent: 3689480 (1972-09-01), Christensen et al.
patent: 3689673 (1972-09-01), Phares
patent: 3694447 (1972-09-01), Pagano
patent: 3751562 (1973-08-01), Nichols
patent: 3888782 (1975-06-01), Boghosian
patent: 3932607 (1976-01-01), Hesselgren
Quesnel et al., Journal of Applied Bact. 45, pp. 397-405 (1978).
Doke et al., Antibiotics & Chemotherapy, 8, (7), pp. 342-348 (1958).
Richards et al., J. of Pharmacy & Pharmacology, 24th Supp., 159-160 (1972).
Richards et al., Pharm. Journal, 210, 118-120 (1973).
Clarke et al.--Med. J. of Australia, 1971, 446 (1971).
Clarke--Med. J. of Australia, 1975, 1, 413-5 (1975).
Lowbury et al., British Med. J., 1, 493-6 (1976).

Affiliated with

Also associated with

Rating

Chlorhexidine salts and compositions of same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chlorhexidine salts and compositions of same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chlorhexidine salts and compositions of same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1564996