Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1985-09-27
1986-08-26
Kight, John
Drug, bio-affecting and body treating compositions
Lymphokine
424 86, 424 88, 260112R, 260112B, 435 7, 435188, 436547, 436543, 530405, 530402, A61K 3900, G01N 5300
Patent
active
046082522
ABSTRACT:
Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxo-carbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.
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Hamburger et al., Chloramphenicol-Specific Antibody Reactivity to Analogs of Chloramphenicol, Immunology, 1969, V. 17, pp. 587-591.
Hamburger, Chloramphenicol-Specific Antibody, Science, 1966, V. 152, pp. 203-205.
Khanna Pyare
Singh Prithipal
Snyder Evan S.
Kight John
Leitereg Theodore J.
Nutter Nathan M.
Rowland Bertram I.
Syntex (U.S.A.) Inc.
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