Chloramphenicol derivatives, antigens and antibodies

Details Chloramphenicol derivatives, antigens and antibodies Chloramphenicol derivatives, antigens and antibodies

1983-05-18

1985-01-29

Kight, John

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 260121, 560 43, 564212, 564213, 435177, A61K 3104

Patent

active

044964790

ABSTRACT:
Chloramphenicol derivatives are provided for use in preparing antigen conjugates for the production of antibodies specific for chloramphenicol. Specifically, the aryl group is derivatized with a side chain functionalized to provide for a carbonyl functionality to react with amino groups of a poly(amino acid). The conjugate is then injected into a vertebrate for production of antisera which are isolated in conventional ways and find particular use in competitive protein binding assays.

REFERENCES:
patent: 2483884 (1949-10-01), Crooks, Jr. et al.
patent: 2483885 (1949-10-01), Crooks, Jr. et al.
patent: 4177038 (1979-12-01), Biebricher et al.

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