Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1981-09-28
1984-12-18
Rosen, Sam
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 26, 435188, 435810, 260121, 260112B, 260112R, G01N 3354, C12Q 132, C12N 996, C07G 700
Patent
active
044891571
ABSTRACT:
Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and finds particular use in competitive protein binding assays.
REFERENCES:
patent: 2483885 (1949-10-01), Crooks et al.
patent: 3817837 (1974-06-01), Rubenstein et al.
Hamburger et al., Chloramphenicol-Specific Antibody II Reactivity to Analogs of Chloramphenicol Immunology, 1969, vol. 17, pp. 587-591.
Khanna Pyare L.
Singh Prithipal
Snyder Evan S.
Foley Shawn P.
Leitereg Theodore J.
Rosen Sam
Rowland Bertram I.
Syva Company
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