Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1981-04-23
1984-12-18
Rosen, Sam
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 26, 435188, 435810, 260121, 260112B, 260112R, G01N 3354, C12Q 132, C12N 996, C07G 700
Patent
active
044891563
ABSTRACT:
Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.
REFERENCES:
patent: 3817837 (1974-06-01), Rubenstein et al.
Hamburger et al., Chloramphenicol-Specific Antibody Differential Antibody Decay Rates to Separate Determinants on One Antigen, Immunology, 1969, V. 17, pp. 593-598.
Hamburger et al., Chloramphenicol-Specific Antibody Neutralization of Antibiotic Effect on Escherichia coli, Immunology, 1969, V. 17, pp. 599-602.
Hamburger et al., Chloramphenicol Specific Antibody A Method for the Detection of Anti-Chloramphenicol Antibody in Human Serum, Immunology, 1971, V. 20, pp. 233-239.
Hamburger, Chloramphenicol-Specific Antibody, Science 1966, V. 152, pp. 203-205.
Hamburger et al., Chloramphenicol-Specific Antibody Reactivity to Analogs of Chloramphenicol, Immunology, 1969, V. 17, pp. 587-591.
Khanna Pyare
Singh Prithipal
Snyder Evan S.
Foley Shawn P.
Leitereg Theodore J.
Rosen Sam
Rowland Bertram I.
Syva Company
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