Chloramphenicol derivatives

Details Chloramphenicol derivatives Chloramphenicol derivatives

1984-11-30

1985-10-01

Kight, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562426, 562433, 564212, 564213, 568423, 568424, C07C 8764, C07C10144

Patent

active

045447659

ABSTRACT:
Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.

REFERENCES:
patent: 2483884 (1949-10-01), Crooks, Jr. et al.
patent: 2483885 (1949-10-01), Crooks, Jr. et al.
patent: 2538764 (1951-01-01), Crooks, Jr. et al.
patent: 2686788 (1954-08-01), Moore et al.
patent: 3592949 (1971-07-01), Teach et al.
patent: 4214001 (1980-07-01), Engelhardt et al.

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