Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-01-30
2007-01-30
Crane, L. E. (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S025330, C536S025340
Reexamination Certificate
active
10403692
ABSTRACT:
A process of manufacturing oligonucleotides includes a 5′-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chloral adducts.
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Capaldi Daniel
Gaus Hans
Krotz Achim
Turney Brett
Crane L. E.
Isis Patent Department
Isis Pharmaceuticals , Inc.
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