Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2011-03-22
2011-03-22
Nickol, Gary B (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S069700, C435S252300, C435S320100, C536S023100, C536S023400, C536S023700, C424S263100
Reexamination Certificate
active
07910329
ABSTRACT:
The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides ofChlamydia trachomatis, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of theChlamydia trachomatisgenome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosingChlamydia trachomatisinfection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides. The invention finally comprises, pharmaceutical, in particular vaccine, compositions for the prevention and/or treatment of bacterial, in particularChlamydia trachomatis, infections.
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Fletcher Leah D.
Griffais Rémy
Hoiseth Susan K.
Metcalf Benjamin J.
Peek Joel A.
Baskar Padma V
Nickol Gary B
Saliwanchik Lloyd & Eisenschenk
Serono Genetics Institute S.A.
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