Chlamydia PMP proteins, gene sequences and uses thereof

Details Chlamydia PMP proteins, gene sequences and uses thereof Chlamydia PMP proteins, gene sequences and uses thereof

2007-07-20

2010-12-14

Ford, Vanessa L. (Department: 1645)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C424S184100, C424S263100

Reexamination Certificate

active

07851609

ABSTRACT:
The invention discloses theChlamydiaPMPE and PMPI polypeptide, polypeptides derived therefrp, (PMP-derived polypeptides), nucleotide sequences encoding said polypeptides, antibodies that specifically bind the PMP polypeptides and PMP-derived polypeptides and T-cells specific for PMP polypeptides and PMP-derived polypeptides. Also disclosed are prophylactic and therapeutic compositions, including immunogenic compositions, e.g., vaccines, comprising PMP polypeptides or PMP-derived polypeptides or antibodies thereto. The invention additionally discloses methods of inducing in animals an immune response toChlamydiacells,Chlamydiaelementary bodies, and/or cells expressing Chlamydial proteins, e.g., cell infected withChlamydia.

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