Chlamydia major outer membrane protein

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 243, 536 2432, 536 2433, 435 6, 435 912, 4353201, 4352402, 43525411, 4352542, 4351723, 435 691, 530300, 530350, C07H 2102, C07H 2104, C07K 500, C07K 1300

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057707146

ABSTRACT:
Methods and compositions are provided for the production of a polypeptide which is immunologically cross-reactive with a naturally-occurring major outer membrane protein (MOMP) of Chlamydia trachomatis. A DNA construct including a replication system recognized by E. coli, and an MOMP gene under the transcriptional control of a .beta.-galactosidase promoter and terminator is provided. Recombinant phage .lambda.gt11/L2/33 was deposited at the American Type Culture Collection, 12301 Parklawn Drive, Rockville, Md. 20852, on Jan. 10, 1985 and granted accession no. 40157. L2 B9-F DNA was deposited at the American Type Culture Collection on Dec. 31, 1985, and granted accession No. 40217.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
Allan et al. Infection and Immunology 45:637-641, 1984.
Keller and Manak, In DNA Probes, Stockton Press, pp. 525-562, 1993.

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