Chlamydia assay employing base treatment

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436510, 436825, 436811, G01N 33569, G01N 33571

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active

049160575

ABSTRACT:
An immunoassay procedure for the detection of chlamydia trachomatis antigen in a urogenital clinical specimen including a method for substantially eliminating the occurrence of false negative and false positive results of the immunoassay procedure. The method comprises treating a patent specimen with an aqueous solution having a final concentration of 0.1M NaOH or 0.1M KOH and then neutralizing the specimen-containing solution before conducting the immunoassay.

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patent: 4617264 (1986-10-01), Whiteley et al.
patent: 4652518 (1987-03-01), Makela et al.
patent: 4663291 (1987-05-01), Rose
patent: 4766065 (1988-08-01), Mosier et al.
The Manual of Clinical Microbiology, pp. 163-164 (3rd Ed. 1980).

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